The domain within your query sequence starts at position 685 and ends at position 745; the E-value for the DEXDc domain shown below is 4e-16.

FSSKTKPADEQSIYEKERIAHAKQIIKPFILRRVKEEVLKLLPPKKDRIELCAMSEKQEQ
L

The domain was found using the schnipsel database

DEXDc

DEAD-like helicases superfamily

• SMART accession number: SM00487
• Description: -
• Interpro abstract (IPR014001):

  Helicases have been classified in 5 superfamilies (SF1-SF5). All of the proteins bind ATP and, consequently, all of them carry the classical Walker A (phosphate-binding loop or P-loop) and Walker B (Mg2+-binding aspartic acid) motifs. For the two largest groups, commonly referred to as SF1 and SF2, a total of seven characteristic motifs has been identified [ (PUBMED:2546125) ]. These two superfamilies encompass a large number of DNA and RNA helicases from archaea, eubacteria, eukaryotes and viruses that seem to be active as monomers or dimers. RNA and DNA helicases are considered to be enzymes that catalyze the separation of double-stranded nucleic acids in an energy-dependent manner [ (PUBMED:11839499) ].

  The various structures of SF1 and SF2 helicases present a common core with two alpha-beta RecA-like domains [ (PUBMED:11839499) (PUBMED:11087862) ]. The structural homology with the RecA recombination protein covers the five contiguous parallel beta strands and the tandem alpha helices. ATP binds to the amino proximal alpha-beta domain, where the Walker A (motif I) and Walker B (motif II) are found. The N-terminal domain also contains motif III (S-A-T) which was proposed to participate in linking ATPase and helicase activities. The carboxy-terminal alpha-beta domain is structurally very similar to the proximal one even though it is bereft of an ATP-binding site, suggesting that it may have originally arisen through gene duplication of the first one.

  Some members of helicase superfamilies 1 and 2 are listed below:

  • DEAD-box RNA helicases. The prototype of DEAD-box proteins is the translation initiation factor eIF4A. The eIF4A protein is an RNA-dependent ATPase which functions together with eIF4B as an RNA helicase [ (PUBMED:11545728) ].
  • DEAH-box RNA helicases. Mainly pre-mRNA-splicing factor ATP-dependent RNA helicases [ (PUBMED:11545728) ].
  • Eukaryotic DNA repair helicase RAD3/ERCC-2, an ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair of UV-damaged DNA.
  • Eukaryotic TFIIH basal transcription factor complex helicase XPB subunit. An ATP-dependent 3'-5' DNA helicase which is a component of the core-TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. It acts by opening DNA either around the RNA transcription start site or the DNA.
  • Eukaryotic ATP-dependent DNA helicase Q. A DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens.
  • Bacterial and eukaryotic antiviral SKI2-like helicase. SKI2 has a role in the 3'-mRNA degradation pathway, repressing dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly(A).
  • Bacterial DNA-damage-inducible protein G (DinG). A probable helicase involved in DNA repair and perhaps also replication [ (PUBMED:8385320) ].
  • Bacterial primosomal protein N' (PriA). PriA protein is one of seven proteins that make up the restart primosome, an apparatus that promotes assembly of replisomes at recombination intermediates and stalled replication forks.
  • Bacterial ATP-dependent DNA helicase recG. It has a critical role in recombination and DNA repair, helping process Holliday junction intermediates to mature products by catalyzing branch migration. It has a DNA unwinding activity characteristic of helicases with a 3' to 5' polarity.
  • A variety of DNA and RNA virus helicases and transcription factors

  This entry represents the DNA-binding domain of classical SF1 and SF2 helicases. It does not recognize bacterial DinG and eukaryotic Rad3 which differ from other SF1-SF2 helicases by the presence of a large insert after the Walker A (see IPR014013 ).

There are 499956 DEXDc domains in 496764 proteins in SMART's nrdb database.

Disease (disease genes where sequence variants are found in this domain)

SwissProt sequences and OMIM curated human diseases associated with missense mutations within the DEXDc domain.

Protein	Disease
DNA excision repair protein ERCC-6 (Q03468) (SMART)	OMIM:133540: Cockayne syndrome-2, type B ; Cerebrooculofacioskeletal syndrome OMIM:214150:
Bloom syndrome protein (P54132) (SMART)	OMIM:210900: Bloom syndrome OMIM:604610: Bloom syndrome OMIM:210900:
Transcriptional regulator ATRX (P46100) (SMART)	OMIM:300032: Alpha-thalassemia/mental retardation syndrome OMIM:301040: Juberg-Marsidi syndrome OMIM:309590: Sutherland-Haan syndrome OMIM:309470: Smith-Fineman-Myers syndrome OMIM:309580:

Metabolism (metabolic pathways involving proteins which contain this domain)

% proteins involved	KEGG pathway ID	Description
42.61	map00500	Starch and sucrose metabolism
42.61	map00790	Folate biosynthesis
8.48	map00230	Purine metabolism
5.29	map03090	Type II secretion system
0.50	map04310	Wnt signaling pathway
0.20	map03060	Protein export
0.10	map00970	Aminoacyl-tRNA biosynthesis
0.10	map03020	RNA polymerase
0.10	map00330	Arginine and proline metabolism

This information is based on mapping of SMART genomic protein database to KEGG orthologous groups. Percentage points are related to the number of proteins with DEXDc domain which could be assigned to a KEGG orthologous group, and not all proteins containing DEXDc domain. Please note that proteins can be included in multiple pathways, ie. the numbers above will not always add up to 100%.

Structure (3D structures containing this domain)

3D Structures of DEXDc domains in PDB

PDB code	Title
1a1v	HEPATITIS C VIRUS NS3 HELICASE DOMAIN COMPLEXED WITH SINGLE STRANDED SDNA
1c4o	CRYSTAL STRUCTURE OF THE DNA NUCLEOTIDE EXCISION REPAIR ENZYME UVRB FROM THERMUS THERMOPHILUS
1cu1	CRYSTAL STRUCTURE OF AN ENZYME COMPLEX FROM HEPATITIS C VIRUS
1d2m	UVRB PROTEIN OF THERMUS THERMOPHILUS HB8; A NUCLEOTIDE EXCISION REPAIR ENZYME
1d9x	CRYSTAL STRUCTURE OF THE DNA REPAIR PROTEIN UVRB
1d9z	CRYSTAL STRUCTURE OF THE DNA REPAIR PROTEIN UVRB IN COMPLEX WITH ATP
1fuu	YEAST INITIATION FACTOR 4A
1gku	Reverse gyrase from Archaeoglobus fulgidus
1gl9	Archaeoglobus fulgidus reverse gyrase complexed with ADPNP
1gm5	Structure of RecG bound to three-way DNA junction
1hei	STRUCTURE OF THE HEPATITIS C VIRUS RNA HELICASE DOMAIN
1hv8	CRYSTAL STRUCTURE OF A DEAD BOX PROTEIN FROM THE HYPERTHERMOPHILE METHANOCOCCUS JANNASCHII
1oyw	Structure of the RecQ Catalytic Core
1oyy	Structure of the RecQ Catalytic Core bound to ATP-gamma-S
1q0u	Crystal Structure of the BstDEAD N-terminal Domain
1qde	CRYSTAL STRUCTURE OF THE ATPASE DOMAIN OF TRANSLATION INITIATION FACTOR 4A FROM SACCHAROMYCES CEREVISIAE-THE PROTOTYPE OF THE DEAD BOX PROTEIN FAMILY
1qva	YEAST INITIATION FACTOR 4A N-TERMINAL DOMAIN
1rif	Crystal structure of the UvsW helicase from Bacteriophage T4
1s2m	Crystal Structure of the DEAD box protein Dhh1p
1t5l	Crystal structure of the DNA repair protein UvrB point mutant Y96A revealing a novel fold for domain 2
1t6n	Crystal structure of the N-terminal domain of human UAP56
1vec	Crystal structure of the N-terminal domain of rck/p54, a human DEAD-box protein
1wp9	Crystal structure of Pyrococcus furiosus Hef helicase domain
1wrb	Crystal structure of the N-terminal RecA-like domain of DjVLGB, a pranarian Vasa-like RNA helicase
1xti	Structure of Wildtype human UAP56
1xtj	structure of human UAP56 in complex with ADP
1xtk	structure of DECD to DEAD mutation of human UAP56
1yks	Crystal structure of yellow fever virus NS3 helicase
1z3i	Structure of the SWI2/SNF2 chromatin remodeling domain of eukaryotic Rad54
1z63	Sulfolobus solfataricus SWI2/SNF2 ATPase core in complex with dsDNA
1z6a	Sulfolobus solfataricus SWI2/SNF2 ATPase core domain
2bhr	Dengue virus RNA helicase
2bmf	Dengue virus RNA helicase at 2.4A
2d7d	Structural insights into the cryptic DNA dependent ATP-ase activity of UvrB
2db3	Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa
2eyq	Crystal structure of Escherichia coli transcription-repair coupling factor
2f55	Two hepatitis c virus ns3 helicase domains complexed with the same strand of dna
2fdc	Structural Basis of DNA Damage Recognition and Processing by UvrB: crystal structure of a UvrB/DNA complex
2fwr	Structure of Archaeoglobus Fulgidis XPB
2fz4	Crystal Structure of the N-terminal half of Archaeoglobus Fulgidus XPB
2g9n	Structure of the DEAD domain of Human eukaryotic initiation factor 4A, eIF4A
2gxq	HERA N-terminal domain in complex with AMP, crystal form 1
2gxs	HERA N-terminal domain in complex with AMP, crystal form 2
2gxu	HERA N-terminal domain in complex with orthophosphate, crystal form 1
2hxy	Crystal structure of human apo-eIF4AIII
2hyi	Structure of the human exon junction complex with a trapped DEAD-box helicase bound to RNA
2i4i	Crystal Structure of human DEAD-box RNA helicase DDX3X
2j0q	The crystal structure of the Exon Junction Complex at 3.2 A resolution
2j0s	The crystal structure of the Exon Junction Complex at 2.2 A resolution
2j0u	The crystal structure of eIF4AIII-Barentsz complex at 3.0 A resolution
2jlq	Dengue virus 4 NS3 helicase structure, apo enzyme.
2jlr	Dengue virus 4 NS3 helicase in complex with AMPPNP
2jls	Dengue virus 4 NS3 helicase in complex with ADP
2jlu	Dengue virus 4 NS3 helicase in complex with ssRNA
2jlv	Dengue virus 4 NS3 helicase in complex with ssRNA and AMPPNP
2jlw	Dengue virus 4 NS3 helicase in complex with ssRNA2
2jlx	Dengue virus 4 NS3 helicase in complex with ssRNA and ADP-Vanadate
2jly	Dengue virus 4 NS3 helicase in complex with ssRNA and ADP-Phosphate
2jlz	Dengue virus 4 NS3 helicase in complex with ssRNA and ADP
2kbe	solution structure of amino-terminal domain of Dbp5p
2nmv	Damage detection by the UvrABC pathway: Crystal structure of UvrB bound to fluorescein-adducted DNA
2oca	The crystal structure of T4 UvsW
2oxc	Human DEAD-box RNA helicase DDX20, DEAD domain in complex with ADP
2p6r	Crystal structure of superfamily 2 helicase Hel308 in complex with unwound DNA
2p6u	Apo structure of the Hel308 superfamily 2 helicase
2pl3	Human DEAD-box RNA helicase DDX10, DEAD domain in complex with ADP
2qeq	Crystal structure of kunjin virus ns3 helicase
2v1x	Crystal structure of human RECQ-like DNA helicase
2v8o	Structure of the Murray Valley encephalitis virus RNA helicase to 1. 9A resolution
2va8	DNA Repair Helicase Hel308
2vbc	Crystal structure of the NS3 protease-helicase from Dengue virus
2vl7	Structure of S. tokodaii Xpd4
2vso	Crystal Structure of a Translation Initiation Complex
2vsx	Crystal Structure of a Translation Initiation Complex
2w00	Crystal structure of the HsdR subunit of the EcoR124I restriction enzyme in complex with ATP
2whx	A second conformation of the NS3 protease-helicase from dengue virus
2wv9	Crystal Structure of the NS3 protease-helicase from Murray Valley encephalitis virus
2wwy	Structure of human RECQ-like helicase in complex with a DNA substrate
2wzq	Insertion Mutant E173GP174 of the NS3 protease-helicase from dengue virus
2xau	Crystal structure of the Prp43p DEAH-box RNA helicase in complex with ADP
2xb2	Crystal structure of the core Mago-Y14-eIF4AIII-Barentsz-UPF3b assembly shows how the EJC is bridged to the NMD machinery
2xgj	Structure of Mtr4, a DExH helicase involved in nuclear RNA processing and surveillance
2xzl	Upf1-RNA complex
2ykg	Structural insights into RNA recognition by RIG-I
2z0m	Crystal structure of hypothetical ATP-dependent RNA helicase from Sulfolobus tokodaii
2z83	Crystal Structure of Catalytic Domain of Japanese Encephalitis Virus NS3 Helicase/Nucleoside Triphosphatase at a Resolution 1.8
2zj2	Archaeal DNA helicase Hjm apo state in form 1
2zj5	Archaeal DNA helicase Hjm complexed with ADP in form 1
2zj8	Archaeal DNA helicase Hjm apo state in form 2
2zja	Archaeal DNA helicase Hjm complexed with AMPPCP in form 2
2zjo	Crystal structure of hepatitis C virus NS3 helicase with a novel inhibitor
2zu6	crystal structure of the eIF4A-PDCD4 complex
3b6e	Crystal structure of human DECH-box RNA Helicase MDA5 (Melanoma differentiation-associated protein 5), DECH-domain
3b7g	Human DEAD-box RNA helicase DDX20, Conserved domain I (DEAD) in complex with AMPPNP (Adenosine-(Beta,gamma)-imidotriphosphate)
3ber	Human DEAD-box RNA-helicase DDX47, conserved domain I in complex with AMP
3bor	Crystal structure of the DEADc domain of human translation initiation factor 4A-2
3dkp	Human DEAD-box RNA-helicase DDX52, conserved domain I in complex with ADP
3dmq	Crystal structure of RapA, a Swi2/Snf2 protein that recycles RNA polymerase during transcription
3eiq	Crystal structure of Pdcd4-eIF4A
3ews	Human DEAD-box RNA-helicase DDX19 in complex with ADP
3ex7	The crystal structure of EJC in its transition state
3fe2	Human DEAD-BOX RNA helicase DDX5 (P68), conserved domain I in complex with ADP
3fhc	Crystal structure of human Dbp5 in complex with Nup214
3fho	Structure of S. pombe Dbp5
3fht	Crystal structure of human Dbp5 in complex with AMPPNP and RNA
3fmo	Crystal structure of the nucleoporin Nup214 in complex with the DEAD-box helicase Ddx19
3fmp	Crystal structure of the nucleoporin Nup214 in complex with the DEAD-box helicase Ddx19
3g0h	Human dead-box RNA helicase DDX19, in complex with an ATP-analogue and RNA
3h1t	The fragment structure of a putative HsdR subunit of a type I restriction enzyme from Vibrio vulnificus YJ016
3i5x	Structure of Mss116p bound to ssRNA and AMP-PNP
3i5y	Structure of Mss116p bound to ssRNA containing a single 5-BrU and AMP-PNP
3i61	Structure of Mss116p bound to ssRNA and ADP-Beryllium Fluoride
3i62	Structure of Mss116p bound to ssRNA and ADP-Aluminum Fluoride
3iuy	Crystal structure of DDX53 DEAD-box domain
3jcm	3JCM
3jcr	3JCR
3kqh	Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
3kqk	Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
3kql	Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
3kqn	Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
3kqu	Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
3kx2	Crystal structure of Prp43p in complex with ADP
3llm	Crystal Structure Analysis of a RNA Helicase
3ly5	DDX18 dead-domain
3mwj	Q28E mutant of HERA N-terminal RecA-like domain, apo form
3mwk	Q28E mutant of HERA N-terminal RecA-like domain, complex with 8-oxo-AMP
3mwl	Q28E mutant of HERA N-terminal RecA-like domain in complex with 8-OXOADENOSINE
3mwy	Crystal structure of the chromodomain-ATPase portion of the yeast Chd1 chromatin remodeler
3nbf	Q28E mutant of hera helicase N-terminal domain bound to 8-oxo-ADP
3nej	Q28E mutant of Hera RNA helicase N-terminal domain - perfectly twinned hexagonal form
3o8b	Visualizing ATP-dependent RNA Translocation by the NS3 Helicase from HCV
3o8c	Visualizing ATP-dependent RNA Translocation by the NS3 Helicase from HCV
3o8d	Visualizing ATP-dependent RNA Translocation by the NS3 Helicase from HCV
3o8r	Visualizing ATP-dependent RNA Translocation by the NS3 Helicase from HCV
3oiy	Helicase domain of reverse gyrase from Thermotoga maritima
3p4x	Helicase domain of reverse gyrase from Thermotoga maritima
3p4y	Helicase domain of reverse gyrase from Thermotoga maritima - P2 form
3pew	S. cerevisiae Dbp5 L327V bound to RNA and ADP BeF3
3pey	S. cerevisiae Dbp5 bound to RNA and ADP BeF3
3rrm	S. cerevisiae dbp5 l327v bound to nup159, gle1 h337r, ip6 and adp
3rrn	S. cerevisiae dbp5 l327v bound to gle1 h337r and ip6
3rvb	3RVB
3sqw	Structure of Mss116p (NTE deletion) bound to ssRNA and AMP-PNP
3sqx	Structure of Mss116p (NTE and C-tail double deletion) bound to ssRNA and AMP-PNP
3tbk	Mouse RIG-I ATPase Domain
3uwx	Crystal structure of UvrA-UvrB complex
3v4r	Crystal structure of a UvrB dimer-DNA complex
3zd6	Snapshot 1 of RIG-I scanning on RNA duplex
3zd7	Snapshot 3 of RIG-I scanning on RNA duplex
4a15	Crystal structure of an XPD DNA complex
4a2p	Structure of duck RIG-I helicase domain
4a2q	Structure of duck RIG-I tandem CARDs and helicase domain
4a2w	Structure of full-length duck RIG-I
4a36	Structure of duck RIG-I helicase domain bound to 19-mer dsRNA and ATP transition state analogue
4a4d	Crystal structure of the N-terminal domain of the Human DEAD-BOX RNA helicase DDX5 (P68)
4a4z	CRYSTAL STRUCTURE OF THE S. CEREVISIAE DEXH HELICASE SKI2 BOUND TO AMPPNP
4a92	Full-length HCV NS3-4A protease-helicase in complex with a macrocyclic protease inhibitor.
4ay2	Capturing 5' tri-phosphorylated RNA duplex by RIG-I
4b3f	crystal structure of Ighmbp2 helicase
4b3g	crystal structure of Ighmbp2 helicase in complex with RNA
4b6e	Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function
4b6f	Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function
4b71	Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function
4b73	Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function
4b74	Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function
4b75	Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function
4b76	Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function
4be7	MUTANT (K220R) OF THE HSDR SUBUNIT OF THE ECOR124I RESTRICTION ENZYME IN COMPLEX WITH ATP
4beb	MUTANT (K220E) OF THE HSDR SUBUNIT OF THE ECOR124I RESTRICTION ENZYME IN COMPLEX WITH ATP
4bec	MUTANT (K220A) OF THE HSDR SUBUNIT OF THE ECOR124I RESTRICTION ENZYME IN COMPLEX WITH ATP
4bgd	Crystal structure of Brr2 in complex with the Jab1/MPN domain of Prp8
4bpb	STRUCTURAL INSIGHTS INTO RNA RECOGNITION BY RIG-I
4bru	Crystal structure of the yeast Dhh1-Edc3 complex
4brw	Crystal structure of the yeast Dhh1-Pat1 complex
4buj	Crystal structure of the S. cerevisiae Ski2-3-8 complex
4c9b	Crystal structure of eIF4AIII-CWC22 complex
4cbg	4CBG
4cbh	4CBH
4cbi	4CBI
4cbl	4CBL
4cbm	4CBM
4cdg	Crystal structure of the Bloom's syndrome helicase BLM in complex with Nanobody
4cgz	Crystal structure of the Bloom's syndrome helicase BLM in complex with DNA
4ct4	CNOT1 MIF4G domain - DDX6 complex
4ct5	DDX6
4d25	4D25
4d26	4D26
4ddt	Thermotoga maritima reverse gyrase, C2 FORM 2
4ddu	Thermotoga maritima reverse gyrase, C2 FORM 1
4ddv	Thermotoga maritima reverse gyrase, triclinic form
4ddw	Thermotoga maritima reverse gyrase, c-centered orthorhombic form
4ddx	Thermotoga maritima reverse gyrase, primitive monoclinic form
4f91	Brr2 Helicase Region
4f92	Brr2 Helicase Region S1087L
4f93	Brr2 Helicase Region S1087L, Mg-ATP
4gl2	Structural Basis for dsRNA duplex backbone recognition by MDA5
4kbf	two different open conformations of the helicase core of the RNA helicase Hera
4kbg	almost closed conformation of the helicase core of the RNA helicase Hera
4kit	Crystal structure of human Brr2 in complex with the Prp8 Jab1/MPN domain
4ljy	Crystal structure of RNA splicing effector Prp5 in complex with ADP
4lk2	Crystal structure of RNA splicing effector Prp5
4nho	4NHO
4nl4	PriA Helicase Bound to ADP
4nl8	PriA Helicase Bound to SSB C-terminal Tail Peptide
4o3m	Ternary complex of Bloom's syndrome helicase
4ojq	Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Fragment 1 [(5-bromo-1H-indol-3-yl)acetic acid]
4ok3	Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 7 [[1-(3-chlorobenzyl)-1H-indol-3-yl]acetic acid]
4ok5	Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 9 [1-(3-ethynylbenzyl)-1H-indol-3-yl]acetic acid]
4ok6	Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 13 [[1-(2-methoxy-5-nitrobenzyl)-1H-indol-3-yl]acetic acid]
4oks	Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 19 [[6-(3,5-diaminophenyl)-1-(2-methoxy-5-nitrobenzyl)-1H-indol-3-yl]acetic acid]
4on9	4ON9
4px9	4PX9
4pxa	4PXA
4q2c	4Q2C
4q2d	4Q2D
4q47	4Q47
4q48	4Q48
4qu4	4QU4
4s20	4S20
4tmu	4TMU
4tyn	4TYN
4tyw	4TYW
4tyy	4TYY
4tz0	4TZ0
4tz6	4TZ6
4u4c	4U4C
4u7d	4U7D
4w7s	4W7S
4wxp	4WXP
4wxr	4WXR
4xgt	4XGT
4xjx	4XJX
4xqk	4XQK
5a9f	5A9F
5a9j	5A9J
5aga	5AGA
5anr	5ANR
5aor	5AOR
5d0u	5D0U
5dca	5DCA
5dtu	5DTU
5dzr	5DZR
5e02	5E02
5e3h	5E3H
5e4f	5E4F
5e7i	5E7I
5e7j	5E7J
5e7m	5E7M
5elx	5ELX
5f98	5F98
5f9f	5F9F
5f9h	5F9H
5ffj	5FFJ
5ffm	5FFM
5fmf	5FMF
5fps	5FPS
5fpt	5FPT
5fpy	5FPY
5gan	5GAN
5gao	5GAO
5gap	5GAP
5gjb	5GJB
5gjc	5GJC
5gm6	5GM6
5gvr	5GVR
5gvs	5GVS
5hzr	5HZR
5ivw	5IVW
5iy6	5IY6
5iy7	5IY7
5iy8	5IY8
5iy9	5IY9
5jaj	5JAJ
5jb2	5JB2
5jbg	5JBG
5jbj	5JBJ
5jc3	5JC3
5jc7	5JC7
5jcf	5JCF
5jch	5JCH
5jmt	5JMT
5jrz	5JRZ
5jwh	5JWH
5k8i	5K8I
5k8l	5K8L
5k8t	5K8T
5k8u	5K8U
5lb3	5LB3
5lb5	5LB5
5lb8	5LB8
5lba	5LBA
5lj5	5LJ5
5lqw	5LQW
5sva	5SVA
8ohm	CRYSTAL STRUCTURE OF RNA HELICASE FROM GENOTYPE 1B HEPATITIS C VIRUS: MECHANISM OF UNWINDING DUPLEX RNA

Links (links to other resources describing this domain)

• PFAM: SNF2_N
• INTERPRO: IPR014001
• PROSITE: DEAH_ATP_HELICASE