The domain within your query sequence starts at position 403 and ends at position 591; the E-value for the DUF4205 domain shown below is 6.19e-10.



SMART accession number:SM01174
Description: The proteins in this family are uncharacterized but often named FAM188B.
Interpro abstract (IPR025257):

This is a conserved domain found in deubiquitinating enzymes, MINDY-3 and MINDY-4.

Deubiquitinating enzymes (DUBs) remove ubiquitin (Ub) from Ub-conjugated substrates to regulate the functional outcome of ubiquitylation. This entry includes MINDY-3/4. They belong to the MINDY (motif interacting with Ub-containing novel DUB) family (peptidase family C121), whose members are deubiquitinating enzymes releasing Lys48-linked ubiquitin [ (PUBMED:27292798) ].

Family alignment:
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There are 1902 DUF4205 domains in 1902 proteins in SMART's nrdb database.

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