The domain within your query sequence starts at position 447 and ends at position 519; the E-value for the HSA domain shown below is 1.44e-28.



domain in helicases and associated with SANT domains
SMART accession number:SM00573
Description: -
Interpro abstract (IPR014012):

The helicase/SANT-associated (HSA) domain is a predicted DNA-binding domain of ~75 amino acids [ (PUBMED:11779830) ], which is found in the eukaryotic SRCAP/p400/DOM and SNF2/brahma families [ (PUBMED:16024792) ]. While each family has the core sequences that define the HSA domain, they each also have additional sequences that distinguish these families from one another. For example, the sequence HWDY(L/C)EEEM(Q/V) is found in the SRCAP/p400/DOM family, whereas the sequence HQE(Y/F)LNSILQ is found in the SNF2 /brahma family [ (PUBMED:16024792) ]. In addition to the SANT and helicase domains, the HSA domain is also found in association with the bromo domain [ (PUBMED:11779830) ].

Family alignment:
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There are 2158 HSA domains in 2154 proteins in SMART's nrdb database.

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