PDB code | Main view | Title | 1a05 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1a05&file=traces.jpg) | CRYSTAL STRUCTURE OF THE COMPLEX OF 3-ISOPROPYLMALATE DEHYDROGENASE FROM THIOBACILLUS FERROOXIDANS WITH 3-ISOPROPYLMALATE |
1ai2 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1ai2&file=traces.jpg) | ISOCITRATE DEHYDROGENASE COMPLEXED WITH ISOCITRATE, NADP+, AND CALCIUM (FLASH-COOLED) |
1ai3 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1ai3&file=traces.jpg) | ORBITAL STEERING IN THE CATALYTIC POWER OF ENZYMES: SMALL STRUCTURAL CHANGES WITH LARGE CATALYTIC CONSEQUENCES |
1bl5 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1bl5&file=traces.jpg) | ISOCITRATE DEHYDROGENASE FROM E. COLI SINGLE TURNOVER LAUE STRUCTURE OF RATE-LIMITED PRODUCT COMPLEX, 10 MSEC TIME RESOLUTION |
1cm7 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1cm7&file=traces.jpg) | 3-ISOPROPYLMALATE DEHYDROGENASE FROM ESCHERICHIA COLI |
1cnz | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1cnz&file=traces.jpg) | 3-ISOPROPYLMALATE DEHYDROGENASE (IPMDH) FROM SALMONELLA TYPHIMURIUM |
1cw1 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1cw1&file=traces.jpg) | CRYSTAL STRUCTURE OF ISOCITRATE DEHYDROGENASE MUTANT K230M BOUND TO ISOCITRATE AND MN2+ |
1cw4 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1cw4&file=traces.jpg) | CRYSTAL STRUCTURE OF K230M ISOCITRATE DEHYDROGENASE IN COMPLEX WITH ALPHA-KETOGLUTARATE |
1cw7 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1cw7&file=traces.jpg) | LOW TEMPERATURE STRUCTURE OF WILD-TYPE IDH COMPLEXED WITH MG-ISOCITRATE |
1dpz | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1dpz&file=traces.jpg) | STUCTURE OF MODIFIED 3-ISOPROPYLMALATE DEHYDROGENASE AT THE C-TERMINUS, HD711 |
1dr0 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1dr0&file=traces.jpg) | STRUCTURE OF MODIFIED 3-ISOPROPYLMALATE DEHYDROGENASE AT THE C-TERMINUS, HD708 |
1dr8 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1dr8&file=traces.jpg) | STRUCTURE OF MODIFIED 3-ISOPROPYLMALATE DEHYDROGENASE AT THE C-TERMINUS, HD177 |
1g2u | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1g2u&file=traces.jpg) | THE STRUCTURE OF THE MUTANT, A172V, OF 3-ISOPROPYLMALATE DEHYDROGENASE FROM THERMUS THERMOPHILUS HB8 : ITS THERMOSTABILITY AND STRUCTURE. |
1gc8 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1gc8&file=traces.jpg) | THE CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS 3-ISOPROPYLMALATE DEHYDROGENASE MUTATED AT 172TH FROM ALA TO PHE |
1gc9 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1gc9&file=traces.jpg) | THE CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS 3-ISOPROPYLMALATE DEHYDROGENASE MUTATED AT 172TH FROM ALA TO GLY |
1gro | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1gro&file=traces.jpg) | REGULATORY AND CATALYTIC MECHANISMS IN ESCHERICHIA COLI ISOCITRATE DEHYDROGENASE: MULTIPLE ROLES FOR N115 |
1grp | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1grp&file=traces.jpg) | REGULATORY AND CATALYTIC MECHANISMS IN ESCHERICHIA COLI ISOCITRATE DEHYDROGENASE: MULTIPLE ROLES FOR N115 |
1hex | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1hex&file=traces.jpg) | STRUCTURE OF 3-ISOPROPYLMALATE DEHYDROGENASE IN COMPLEX WITH NAD+: LIGAND-INDUCED LOOP-CLOSING AND MECHANISM FOR COFACTOR SPECIFICITY |
1hj6 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1hj6&file=traces.jpg) | ISOCITRATE DEHYDROGENASE S113E MUTANT COMPLEXED WITH ISOPROPYLMALATE, NADP+ AND MAGNESIUM (FLASH-COOLED) |
1hqs | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1hqs&file=traces.jpg) | CRYSTAL STRUCTURE OF ISOCITRATE DEHYDROGENASE FROM BACILLUS SUBTILIS |
1idc | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1idc&file=traces.jpg) | ISOCITRATE DEHYDROGENASE FROM E.COLI (MUTANT K230M), STEADY-STATE INTERMEDIATE COMPLEX DETERMINED BY LAUE CRYSTALLOGRAPHY |
1idd | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1idd&file=traces.jpg) | ISOCITRATE DEHYDROGENASE Y160F MUTANT APO ENZYME |
1ide | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1ide&file=traces.jpg) | ISOCITRATE DEHYDROGENASE Y160F MUTANT STEADY-STATE INTERMEDIATE COMPLEX (LAUE DETERMINATION) |
1idf | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1idf&file=traces.jpg) | ISOCITRATE DEHYDROGENASE K230M MUTANT APO ENZYME |
1idm | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1idm&file=traces.jpg) | 3-ISOPROPYLMALATE DEHYDROGENASE, LOOP-DELETED CHIMERA |
1ika | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1ika&file=traces.jpg) | STRUCTURE OF ISOCITRATE DEHYDROGENASE WITH ALPHA-KETOGLUTARATE AT 2.7 ANGSTROMS RESOLUTION: CONFORMATIONAL CHANGES INDUCED BY DECARBOXYLATION OF ISOCITRATE |
1ipd | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1ipd&file=traces.jpg) | THREE-DIMENSIONAL STRUCTURE OF A HIGHLY THERMOSTABLE ENZYME, 3-ISOPROPYLMALATE DEHYDROGENASE OF THERMUS THERMOPHILUS AT 2.2 ANGSTROMS RESOLUTION |
1iso | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1iso&file=traces.jpg) | ISOCITRATE DEHYDROGENASE: STRUCTURE OF AN ENGINEERED NADP+--> NAD+ SPECIFICITY-REVERSAL MUTANT |
1lwd | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1lwd&file=traces.jpg) | CRYSTAL STRUCTURE OF NADP-DEPENDENT ISOCITRATE DEHYDROGENASE FROM PORCINE HEART MITOCHONDRIA |
1osi | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1osi&file=traces.jpg) | STRUCTURE OF 3-ISOPROPYLMALATE DEHYDROGENASE |
1osj | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1osj&file=traces.jpg) | STRUCTURE OF 3-ISOPROPYLMALATE DEHYDROGENASE |
1p8f | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1p8f&file=traces.jpg) | A four location model to explain the stereospecificity of proteins. |
1pb1 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1pb1&file=traces.jpg) | A four location model to explain the stereospecificity of proteins. |
1pb3 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1pb3&file=traces.jpg) | Sites of binding and orientation in a four location model for protein stereospecificity. |
1sjs | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1sjs&file=traces.jpg) | ACCESS TO PHOSPHORYLATION IN ISOCITRATE DEHYDROGENASE MAY OCCUR BY DOMAIN SHIFTING |
1t09 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1t09&file=traces.jpg) | Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex NADP |
1t0l | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1t0l&file=traces.jpg) | Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP, isocitrate, and calcium(2+) |
1tyo | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1tyo&file=traces.jpg) | Isocitrate Dehydrogenase from the hyperthermophile Aeropyrum pernix in complex with etheno-NADP |
1v53 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1v53&file=traces.jpg) | The crystal structure of 3-isopropylmalate dehydrogenase from Bacillus coagulans |
1v5b | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1v5b&file=traces.jpg) | The Structure Of The Mutant, S225A and E251L, Of 3-Isopropylmalate Dehydrogenase From Bacillus Coagulans |
1v94 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1v94&file=traces.jpg) | Crystal structure of isocitrate dehydrogenase from Aeropyrum pernix |
1vlc | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1vlc&file=traces.jpg) | Crystal structure of 3-isopropylmalate dehydrogenase (TM0556) from Thermotoga maritima at 1.90 A resolution |
1w0d | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1w0d&file=traces.jpg) | The high resolution structure of Mycobacterium tuberculosis LeuB (Rv2995c) |
1wal | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1wal&file=traces.jpg) | 3-ISOPROPYLMALATE DEHYDROGENASE (IPMDH) MUTANT (M219A)FROM THERMUS THERMOPHILUS |
1wpw | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1wpw&file=traces.jpg) | Crystal Structure of IPMDH from Sulfolobus tokodaii |
1x0l | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1x0l&file=traces.jpg) | Crystal structure of tetrameric homoisocitrate dehydrogenase from an extreme thermophile, Thermus thermophilus |
1xaa | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1xaa&file=traces.jpg) | 3-ISOPROPYLMALATE DEHYDROGENASE, LOW TEMPERATURE (100K) STRUCTURE |
1xab | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1xab&file=traces.jpg) | 3-ISOPROPYLMALATE DEHYDROGENASE, LOW TEMPERATURE (150K) STRUCTURE |
1xac | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1xac&file=traces.jpg) | CHIMERA ISOPROPYLMALATE DEHYDROGENASE BETWEEN BACILLUS SUBTILIS (M) AND THERMUS THERMOPHILUS (T) FROM N-TERMINAL: 20% T MIDDLE 20% M RESIDUAL 60% T, MUTATED AT S82R. LOW TEMPERATURE (100K) STRUCTURE. |
1xad | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1xad&file=traces.jpg) | CHIMERA ISOPROPYLMALATE DEHYDROGENASE BETWEEN BACILLUS SUBTILIS (M) AND THERMUS THERMOPHILUS (T) FROM N-TERMINAL: 20% T MIDDLE 20% M RESIDUAL 60% T, MUTATED AT S82R. LOW TEMPERATURE (150K) STRUCTURE. |
1xgv | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1xgv&file=traces.jpg) | Isocitrate Dehydrogenase from the hyperthermophile Aeropyrum pernix |
1xkd | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1xkd&file=traces.jpg) | Ternary complex of Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix |
1zor | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=1zor&file=traces.jpg) | Isocitrate dehydrogenase from the hyperthermophile Thermotoga maritima |
2ayq | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2ayq&file=traces.jpg) | 3-ISOPROPYLMALATE DEHYDROGENASE FROM THE MODERATE FACULTATIVE THERMOPHILE, BACILLUS COAGULANS |
2cmj | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2cmj&file=traces.jpg) | Crystal Structure of Mouse Cytosolic Isocitrate Dehydrogenase |
2cmv | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2cmv&file=traces.jpg) | Crystal Structure of Mouse Cytosolic Isocitrate Dehydrogenase complexed with Cadmium and citrate |
2d1c | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2d1c&file=traces.jpg) | Crystal Structure Of TT0538 protein from Thermus thermophilus HB8 |
2d4v | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2d4v&file=traces.jpg) | Crystal structure of NAD dependent isocitrate dehydrogenase from Acidithiobacillus thiooxidans |
2dht | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2dht&file=traces.jpg) | Crystal structure of isocitrate dehydrogenase from Sulfolobus tokodaii strain7 |
2e0c | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2e0c&file=traces.jpg) | crystal structure of isocitrate dehydrogenase from Sulfolobus tokodaii strain7 at 2.0 A resolution |
2e5m | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2e5m&file=traces.jpg) | Crystal structure of isocitrate dehydrogenase from Sulfolobus tokodaii strain 7 |
2g4o | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2g4o&file=traces.jpg) | anomalous substructure of 3-ISOPROPYLMALATE DEHYDROGENASE |
2iv0 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2iv0&file=traces.jpg) | Thermal stability of isocitrate dehydrogenase from Archaeoglobus fulgidus studied by crystal structure analysis and engineering of chimers. |
2qfv | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2qfv&file=traces.jpg) | Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with NADP(+) |
2qfw | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2qfw&file=traces.jpg) | Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with isocitrate |
2qfx | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2qfx&file=traces.jpg) | Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with NADPH, a-ketoglutarate and Ca(2+) |
2qfy | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2qfy&file=traces.jpg) | Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with a-ketoglutarate |
2uxq | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2uxq&file=traces.jpg) | Isocitrate dehydrogenase from the psychrophilic bacterium Desulfotalea psychrophila: biochemical properties and crystal structure analysis |
2uxr | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2uxr&file=traces.jpg) | Complex with isocitrate and the protein isocitrate dehydrogenase from the psychrophilic bacterium Desulfotalea psychrophila |
2y3z | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2y3z&file=traces.jpg) | Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - apo enzyme |
2y40 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2y40&file=traces.jpg) | Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - complex with Mn |
2y41 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2y41&file=traces.jpg) | Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - complex with IPM and MN |
2y42 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2y42&file=traces.jpg) | Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - complex with NADH and Mn |
2ztw | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=2ztw&file=traces.jpg) | Structure of 3-isopropylmalate dehydrogenase in complex with the inhibitor and NAD+ |
3ah3 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3ah3&file=traces.jpg) | Crystal structure of LR5-1, 3-isopropylmalate dehydrogenase created by directed evolution |
3asj | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3asj&file=traces.jpg) | Crystal structure of homoisocitrate dehydrogenase in complex with a designed inhibitor |
3blv | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3blv&file=traces.jpg) | Yeast Isocitrate Dehydrogenase with Citrate Bound in the Regulatory Subunits |
3blw | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3blw&file=traces.jpg) | Yeast Isocitrate Dehydrogenase with Citrate and AMP Bound in the Regulatory Subunits |
3blx | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3blx&file=traces.jpg) | Yeast Isocitrate Dehydrogenase (Apo Form) |
3dms | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3dms&file=traces.jpg) | 1.65A crystal structure of isocitrate dehydrogenase from Burkholderia pseudomallei |
3flk | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3flk&file=traces.jpg) | Crystal Structure of Tartrate Dehydrogenase from Pseudomonas putida in complex with NADH, oxalate and metal ion |
3fmx | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3fmx&file=traces.jpg) | Crystal structure of Tartrate dehydrogenase from Pseudomonas putida complexed with NADH |
3icd | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3icd&file=traces.jpg) | STRUCTURE OF A BACTERIAL ENZYME REGULATED BY PHOSPHORYLATION, ISOCITRATE DEHYDROGENASE |
3inm | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3inm&file=traces.jpg) | Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase R132H mutant in complex with NADPH, ALPHA-KETOGLUTARATE and CALCIUM(2+) |
3lcb | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3lcb&file=traces.jpg) | The crystal structure of isocitrate dehydrogenase kinase/phosphatase in complex with its substrate, isocitrate dehydrogenase, from Escherichia coli. |
3map | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3map&file=traces.jpg) | Crystal structure of homodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP and isocitrate |
3mar | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3mar&file=traces.jpg) | Crystal structure of homodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP |
3mas | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3mas&file=traces.jpg) | Crystal structure of heterodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP and isocitrate |
3r8w | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3r8w&file=traces.jpg) | Structure of 3-isopropylmalate dehydrogenase isoform 2 from Arabidopsis thaliana at 2.2 angstrom resolution |
3ty3 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3ty3&file=traces.jpg) | Crystal structure of homoisocitrate dehydrogenase from Schizosaccharomyces pombe bound to glycyl-glycyl-glycine |
3ty4 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3ty4&file=traces.jpg) | Crystal structure of homoisocitrate dehydrogenase from Schizosaccharomyces pombe |
3u1h | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3u1h&file=traces.jpg) | Crystal structure of IPMDH from the last common ancestor of Bacillus |
3udo | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3udo&file=traces.jpg) | Crystal structure of putative isopropylamlate dehydrogenase from Campylobacter jejuni |
3udu | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3udu&file=traces.jpg) | Crystal structure of putative 3-isopropylmalate dehydrogenase from Campylobacter jejuni |
3us8 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3us8&file=traces.jpg) | Crystal Structure of an isocitrate dehydrogenase from Sinorhizobium meliloti 1021 |
3vkz | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3vkz&file=traces.jpg) | 3-isopropylmalate dehydrogenase from Shewanella oneidensis MR-1 at atmospheric pressure |
3vl2 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3vl2&file=traces.jpg) | 3-isopropylmalate dehydrogenase from Shewanella oneidensis MR-1 at 160 MPa |
3vl3 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3vl3&file=traces.jpg) | 3-isopropylmalate dehydrogenase from Shewanella oneidensis MR-1 at 340 MPa |
3vl4 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3vl4&file=traces.jpg) | 3-isopropylmalate dehydrogenase from Shewanella oneidensis MR-1 at 410 MPa |
3vl6 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3vl6&file=traces.jpg) | 3-isopropylmalate dehydrogenase from Shewanella oneidensis MR-1 at 580 MPa |
3vl7 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3vl7&file=traces.jpg) | 3-isopropylmalate dehydrogenase from Shewanella oneidensis MR-1 at 650 MPa |
3vmj | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3vmj&file=traces.jpg) | 3-isopropylmalate dehydrogenase from Shewanella oneidensis MR-1 |
3vmk | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3vmk&file=traces.jpg) | 3-isopropylmalate dehydrogenase from Shewanella benthica DB21 MT-2 |
3vml | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3vml&file=traces.jpg) | Chimera 3-isopropylmalate dehydrogenase between Shewanella oneidensis MR-1 (O) and Shewanella benthica DB21 MT-2 (M) from N-terminal: 20% O middle 70% M residual 10% O |
3wzv | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3wzv&file=traces.jpg) | 3WZV |
3wzw | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3wzw&file=traces.jpg) | 3WZW |
3wzx | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3wzx&file=traces.jpg) | 3WZX |
3wzy | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=3wzy&file=traces.jpg) | 3WZY |
4aj3 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4aj3&file=traces.jpg) | 3D structure of E. coli Isocitrate Dehydrogenase in complex with Isocitrate, calcium(II) and NADP - The pseudo-Michaelis complex |
4aja | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4aja&file=traces.jpg) | 3D structure of E. coli Isocitrate Dehydrogenase in complex with Isocitrate, calcium(II) and thioNADP |
4ajb | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4ajb&file=traces.jpg) | 3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with Isocitrate, calcium(II) and thioNADP |
4ajc | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4ajc&file=traces.jpg) | 3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, calcium(II) and adenine nucleotide phosphate |
4ajr | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4ajr&file=traces.jpg) | 3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, magnesium(II) and NADPH - The product complex |
4ajs | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4ajs&file=traces.jpg) | 3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with isocitrate, magnesium(II), Adenosine 2',5'-biphosphate and ribosylnicotinamide-5'-phosphate |
4aou | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4aou&file=traces.jpg) | CtIDH bound to NADP. The complex structures of Isocitrate dehydrogenase from Clostridium thermocellum and Desulfotalea psychrophila, support a new active site locking mechanism |
4aov | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4aov&file=traces.jpg) | DpIDH-NADP. The complex structures of Isocitrate dehydrogenase from Clostridium thermocellum and Desulfotalea psychrophila, support a new active site locking mechanism |
4aoy | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4aoy&file=traces.jpg) | Open CtIDH. The complex structures of Isocitrate dehydrogenase from Clostridium thermocellum and Desulfotalea psychrophila, support a new active site locking mechanism |
4bnp | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4bnp&file=traces.jpg) | 3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with isocitrate and magnesium(II) |
4f7i | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4f7i&file=traces.jpg) | Structure of Isopropylmalate dehydrogenase from Thermus thermophilus in complex with IPM, Mn and NADH |
4hcx | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4hcx&file=traces.jpg) | Structure of ICDH-1 from M.tuberculosis complexed with NADPH & Mn2+ |
4i3k | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4i3k&file=traces.jpg) | Crystal structure of a metabolic reductase with 1-hydroxy-6-(4-hydroxybenzyl)-4-methylpyridin-2(1H)-one |
4i3l | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4i3l&file=traces.jpg) | Crystal structure of a metabolic reductase with 6-benzyl-1-hydroxy-4-methylpyridin-2(1H)-one |
4icd | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4icd&file=traces.jpg) | REGULATION OF ISOCITRATE DEHYDROGENASE BY PHOSPHORYLATION INVOLVES NO LONG-RANGE CONFORMATIONAL CHANGE IN THE FREE ENZYME |
4iwh | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4iwh&file=traces.jpg) | Crystal structure of a 3-isopropylmalate dehydrogenase from Burkholderia pseudomallei |
4ja8 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4ja8&file=traces.jpg) | Complex of Mitochondrial Isocitrate Dehydrogenase R140Q Mutant with AGI-6780 Inhibitor |
4kzo | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4kzo&file=traces.jpg) | Crystal Structure Analysis of human IDH1 mutants in complex with NADP+ and Ca2+/alpha-Ketoglutarate |
4l03 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4l03&file=traces.jpg) | Crystal Structure Analysis of human IDH1 mutants in complex with NADP+ and Ca2+/alpha-Ketoglutarate |
4l04 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4l04&file=traces.jpg) | Crystal Structure Analysis of human IDH1 mutants in complex with NADP+ and Ca2+/alpha-Ketoglutarate |
4l06 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4l06&file=traces.jpg) | Crystal Structure Analysis of human IDH1 mutants in complex with NADP+ and Ca2+/alpha-Ketoglutarate |
4p69 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4p69&file=traces.jpg) | 4P69 |
4umx | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4umx&file=traces.jpg) | 4UMX |
4umy | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4umy&file=traces.jpg) | 4UMY |
4wuo | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4wuo&file=traces.jpg) | 4WUO |
4xrx | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4xrx&file=traces.jpg) | 4XRX |
4xs3 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4xs3&file=traces.jpg) | 4XS3 |
4xxv | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4xxv&file=traces.jpg) | 4XXV |
4y1p | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4y1p&file=traces.jpg) | 4Y1P |
4yb4 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=4yb4&file=traces.jpg) | 4YB4 |
5de1 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=5de1&file=traces.jpg) | 5DE1 |
5icd | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=5icd&file=traces.jpg) | REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE |
5j32 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=5j32&file=traces.jpg) | 5J32 |
5j33 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=5j33&file=traces.jpg) | 5J33 |
5j34 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=5j34&file=traces.jpg) | 5J34 |
5k10 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=5k10&file=traces.jpg) | 5K10 |
5k11 | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=5k11&file=traces.jpg) | 5K11 |
6icd | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=6icd&file=traces.jpg) | REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE |
7icd | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=7icd&file=traces.jpg) | REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE |
8icd | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=8icd&file=traces.jpg) | REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE |
9icd | ![](http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/getimg.pl?source=pdbsum&pdb_code=9icd&file=traces.jpg) | CATALYTIC MECHANISM OF NADP+-DEPENDENT ISOCITRATE DEHYDROGENASE: IMPLICATIONS FROM THE STRUCTURES OF MAGNESIUM-ISOCITRATE AND NADP+ COMPLEXES |