The domain within your query sequence starts at position 28 and ends at position 183; the E-value for the LIF_OSM domain shown below is 7.44e-92.



leukemia inhibitory factor
SMART accession number:SM00080
Description: OSM, Oncostatin M
Interpro abstract (IPR001581):

On the basis of functional and structural similarities, the small cytokines leukemia inhibitory factor (LIF) and oncostatin (OSM) can be classified into a single family [ (PUBMED:1566332) (PUBMED:1717982) ].

It has been said [ (PUBMED:1717982) ] that LIF and OSM can be included in the IL-6 family of cytokines, but while all these cytokines seem to be structurally related, the sequence similarity is not high enough to allow the use of a single consensus pattern.

GO process:immune response (GO:0006955)
GO component:extracellular region (GO:0005576)
GO function:cytokine activity (GO:0005125)
Family alignment:
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There are 186 LIF_OSM domains in 186 proteins in SMART's nrdb database.

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