 Mago-bindMago binding | |
|---|---|
| SMART ACC: | SM001273 |
| Description: | Members of this family adopt a structure consisting of a small globular all-beta-domain, with a three-stranded beta-sheet and a contiguous beta-hairpin. They bind to Mago alpha-helices via extensive electrostatic interactions and at a beta2-beta3 loop via hydrophobic interactions PMID:14968132. |
| InterPro ACC: | IPR015362 |
| InterPro abstract: | Partner of Y14 and mago (PYM, also known as WIBG) is a key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or … expand |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 1 405 Mago-bind domains in 1 383 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing Mago-bind domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing Mago-bind domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a Mago-bind domain which could be assigned to a KEGG orthologous group, and not all proteins containing Mago-bind domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.