The domain within your query sequence starts at position 217 and ends at position 326; the E-value for the 2k2w domain shown below is 3e-32.
ERKQIFKGKTFVFLNAKQHKKLSSAVAFGGGEARLMAEDDEEEQSFFSAPGTCVVDVGIT NTQLIISHSQKKWIHLIMDTLQRNGLRPIPEAEIGLAVIFMTTENYCNPQ