The domain within your query sequence starts at position 48 and ends at position 224; the E-value for the 2yop domain shown below is 4e-44.
IRSTKPPRYKCGISKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINIA LVNGKTGEVIDTKFFDMWGGDVAPFIEFLKTIQDGTVVLMATYDDGATKLTDEARRLIAE LGSTSITSLGFRDNWVFCGGKGIKTKSPFEQHIKNNKETNKYEGWPEVVEMEGCIPQ