SMART: Pfam domain ACT

The domain within your query sequence starts at position 71 and ends at position 138; the E-value for the ACT_7 domain shown below is 1.3e-19.

VAEATWLVMNVSHSGSVVQAAGVTKIARSVIAPLAEHHVSVLMLSTYQTDFILVREQDLS
VVIHTLAQ

ACT_7

PFAM accession number:	PF13840
Interpro abstract (IPR027795):	The ACT domain is a structural motif of 70-90 amino acids that functions in the control of metabolism, solute transport and signal transduction. They are thus found in a variety of different proteins in a variety of different arrangements [ (PUBMED:16987805) ]. In mammalian phenylalanine hydroxylase the domain forms no contacts but promotes an allosteric effect despite the apparent lack of ligand binding [ (PUBMED:18368466) ]. This ACT domain is found in CASTOR proteins IPR026249 and C-terminal in some aspartate kinases.

PFAM accession number:

PF13840

Interpro abstract (IPR027795):

The ACT domain is a structural motif of 70-90 amino acids that functions in the control of metabolism, solute transport and signal transduction. They are thus found in a variety of different proteins in a variety of different arrangements [ (PUBMED:16987805) ]. In mammalian phenylalanine hydroxylase the domain forms no contacts but promotes an allosteric effect despite the apparent lack of ligand binding [ (PUBMED:18368466) ].

This ACT domain is found in CASTOR proteins IPR026249 and C-terminal in some aspartate kinases.

This is a PFAM domain. For full annotation and more information, please see the PFAM entry ACT_7