The domain within your query sequence starts at position 75 and ends at position 439; the E-value for the AMH_N domain shown below is 3e-133.
NSYEYAFLEAVQESRWGPQDLATFGVCSTDSQATLPALQRLGAWLGETGEQQLLVLHLAE VIWEPELLLKFQEPPPGGASRWEQALLVLYPGPGPQVTVTGTGLRGTQNLCPTRDTRYLV LTVDFPAGAWSGSGLILTLQPSREGATLSIDQLQAFLFGSDSRCFTRMTPTLVVLPPAEP SPQPAHGQLDTMPFPQPGLSLEPEALPHSADPFLETLTRLVRALRGPLTQASNTQLALDP GALASFPQGLVNLSDPAALGRLLDWEEPLLLLLSPAAATEREPMPLHGPASAPWAAGLQR RVAVELQAAASELRDLPGLPPTAPPLLARLLALCPNDSRSSGDPLRALLLLKALQGLRAE WHGRE
AMH_N |
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PFAM accession number: | PF04709 |
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Interpro abstract (IPR006799): | Anti-Mullerian hormone, AMH is a signalling molecule involved in male and female sexual differentiation [ (PUBMED:1782869) ]. Defects in synthesis or action of AMH cause persistent Mullerian duct syndrome (PMDS), a rare form of male pseudohermaphroditism [ (PUBMED:8162013) ]. This family represents the N-terminal part of the protein, which is not thought to be essential for activity [ (PUBMED:8162013) ]. AMH contains a TGF-beta domain ( IPR001839 ), at the C terminus. |
GO process: | gonad development (GO:0008406) |
GO function: | growth factor activity (GO:0008083) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry AMH_N