The domain within your query sequence starts at position 1120 and ends at position 1135; the E-value for the APC_15aa domain shown below is 9.9e-9.
EEERPTNYSIKYNEEK
APC_15aa |
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| PFAM accession number: | PF05972 |
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| Interpro abstract (IPR009240): | The 15 aa repeat is found in the APC protein family. It is involved in binding beta-catenin [ (PUBMED:9823329) ] along with the IPR009223 repeats. Many human cancer mutations map to the region around these motifs, and may be involved in disrupting their binding of beta-catenin. |
| GO process: | Wnt signaling pathway (GO:0016055) |
| GO function: | beta-catenin binding (GO:0008013) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry APC_15aa