The domain within your query sequence starts at position 9 and ends at position 73; the E-value for the AXIN1_TNKS_BD domain shown below is 8.1e-27.



PFAM accession number:PF16646
Interpro abstract (IPR032101):

This is the N-terminal tankyrase binding domain described for Axin-1 [ (PUBMED:22307604) ].

Axin (axis inhibition protein) is a scaffold protein that is involved in many signalling pathways, including the Wnt, transforming growth factor-beta, MAP kinase pathways, as well as p53 activation cascades [ (PUBMED:18316368) (PUBMED:15067197) ]. It controls many biological processes ranging from sugar intake, cell proliferation, and organ development to cell death [ (PUBMED:15067197) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry AXIN1_TNKS_BD