The domain within your query sequence starts at position 18 and ends at position 74; the E-value for the CDC45 domain shown below is 7.9e-24.

RVLLFVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELETAYLEHKEQIKLLIK

CDC45

CDC45
PFAM accession number:PF02724
Interpro abstract (IPR003874):

CDC45 is an essential gene required for initiation of DNA replication in Saccharomyces cerevisiae (cell division control protein 45), forming a complex with MCM5/CDC46. Homologs of CDC45 have been identified in human [ (PUBMED:9660782) ], mouse and the smut fungus, Melampsora spp., (tsd2 protein) among others.

GO process:DNA replication initiation (GO:0006270)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry CDC45