The domain within your query sequence starts at position 2313 and ends at position 2449; the E-value for the CENP-F_leu_zip domain shown below is 1e-46.
DEKKHQNILEQLKESKHHADLLKDRVENLEQELILSEKNMIFQAEKSKAEIQTLKSEIQR MAQNLQDLQLELISTRSENENLMKELKKEQERVSDLETINSSIENLLKDKEQEKVQMKEE AKITVEMLQTQLKELNE
CENP-F_leu_zip |
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PFAM accession number: | PF10473 |
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Interpro abstract (IPR019513): | Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway [ (PUBMED:7542657) (PUBMED:14555653) ]. There are several leucine-rich repeats along the sequence of LEK1 that are considered to be zippers, though they do not appear to be binding DNA directly in this instance [ (PUBMED:14555653) ]. |
GO function: | transcription factor binding (GO:0008134), dynein complex binding (GO:0070840), protein homodimerization activity (GO:0042803) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry CENP-F_leu_zip