The domain within your query sequence starts at position 863 and ends at position 1184; the E-value for the CPSF_A domain shown below is 4.3e-104.
ASVIRVMNPIQGNTLDLVQLEQNEAAFSVAVCRFSNTGEDWYVLVGVAKDLILSPRSVAG GFVYTYKLVNNGEKLEFLHKTPVEEVPAAIAPFQGRVLIGVGKLLRVYDLGKKKLLRKCE NKHIANYISGIQTIGHRVIVSDVQESFIWVRYKRNENQLIIFADDTYPRWVTTASLLDYD TVAGADKFGNICVVRLPPNTNDEVDEDPTGNKALWDRGLLNGASQKAEVIMNYHVGETVL SLQKTTLIPGGSESLVYTTLSGGIGILVPFTSHEDHDFFQHVEMHLRSEHPPLCGRDHLS FRSYYFPVKNVIDGDLCEQFNS
CPSF_A |
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PFAM accession number: | PF03178 |
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Interpro abstract (IPR004871): | This family includes a region that lies towards the C terminus of the cleavage and polyadenylation specificity factor (CPSF) A (160kDa) subunit. CPSF is involved in mRNA polyadenylation and binds the AAUAAA conserved sequence in pre-mRNA. CPSF has also been found to be necessary for splicing of single-intron pre-mRNAs [ (PUBMED:11421366) ]. The function of the aligned region is unknown but may be involved in RNA/DNA binding. |
GO component: | nucleus (GO:0005634) |
GO function: | nucleic acid binding (GO:0003676) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry CPSF_A