The domain within your query sequence starts at position 250 and ends at position 409; the E-value for the DUF1295 domain shown below is 9.4e-9.

IIHDGFGFMLVFGDLAWVPFTYSLQAQFLLYHPQPLGLPMALLICLLKVIGYYIFRGANS
QKNTFRKNPSDPSVAGLETIPTATGRQLLVSGWWGMVRHPNYLGDLIMALAWSLPCGLSH
LLPYFYVLYFTALLVHREARDEQQCLQKYGRAWQEYCKRV

DUF1295

 DUF1295
PFAM accession number:PF06966
Interpro abstract (IPR010721):

This family contains a number of bacterial and eukaryotic proteins of unknown function that are approximately 300 residues long.

This is a PFAM domain. For full annotation and more information, please see the PFAM entry DUF1295