The domain within your query sequence starts at position 52 and ends at position 279; the E-value for the DUF4589 domain shown below is 2e-97.

EVVSQIDKLTSDFDFELEPDDWTTATVSSTSSSDKAGVGGPFDLGHLDFMTADILSDSWE
FCSFLDVSTPSDSVDGPEAPRPGTGPDYQLMNGGLPIPNGPRVETPDSSSEEAFSAGPAK
GQVPQRTPGTRERVRFSDKVLYHALCCDDEEGDGEEGEEEEEGDLAPELPRVEPHTGPLK
PSPAPYKTKRSPLTTRRLGPTLAPEQTRRVTRNSSTQTVSDKSTQTVL

DUF4589

 DUF4589
PFAM accession number:PF15252
Interpro abstract (IPR027997):

This entry includes protein Largen and INSYN1 (inhibitory synaptic factor 1). Largen regulates cell size control [ (PUBMED:24656129) ]. INSYN1 is part of the complex that mediates postsynaptic inhibition [ (PUBMED:27609886) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry DUF4589