The domain within your query sequence starts at position 147 and ends at position 570; the E-value for the EVC2_like domain shown below is 2.1e-191.
GECYSVSYTASLDPTALGTGESLDLPARLIFQSPSQNRTQLKAPFTITVEEKIMVLPNHG LHAAGFIAAFLISLLLTVAALFFLARGRCLQGGMLSRCRIQHPENKLEPSPFTSANGVSQ DLSLNDQVVAILTSEEPGSMLQALEELEIATLNQADADLEACRNQISKDIIALLMKNLVS GGHLSPQTERKMAAAFKKQFLLLENEIQEEYERKMLALTAECDLEMRKKTENQYQREMVA MEEAEEVLKRVSERSAAECSSLLRTLHGLEQEDMQRSLTLDQAEDFAQAHRQLAVFQRNE LHSIVYTQIQSAVSKGELRPEVAKMMLQDYSKTQESVEELMDFFQATKRYHLSKRFGHRE YLVQRLQAMETRVQGLLNTAATQLTSLIHKHERAGYLDEDQMETLLERAQTETFSIKQKL DNDL
EVC2_like |
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PFAM accession number: | PF12297 |
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Interpro abstract (IPR022076): | Limbin (EVC2) interacts with AVC and is a positive regulator of the hedgehog signaling pathway. It plays a critical role in bone formation and skeletal development and may be involved in early embryonic morphogenesis [ (PUBMED:21356043) ]. |
GO process: | smoothened signaling pathway (GO:0007224) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry EVC2_like