The domain within your query sequence starts at position 1 and ends at position 160; the E-value for the Endonuclease_5 domain shown below is 3.3e-50.



PFAM accession number:PF04493
Interpro abstract (IPR007581):

Endonuclease V is specific for single-stranded DNA, for duplex DNA that contains uracil, or that is damaged [ (PUBMED:8990280) ]. Matrix metalloproteinase-1 (MMP-1) is the major enzyme responsible for collagen 1 digestion. It is induced by exposure to sunlight, but is reduced with treatment of DNA repair enzyme endonuclease V [ (PUBMED:18459971) ]. This family consequently has potential medical importance [ (PUBMED:18328204) ].

This endonuclease also appears in bifunctional enzymes, such as the bifunctional methyltransferase/endonuclease in Thermoplasma acidophilum.

GO process:DNA repair (GO:0006281)
GO function:endonuclease activity (GO:0004519)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Endonuclease_5