The domain within your query sequence starts at position 1 and ends at position 191; the E-value for the FAM101 domain shown below is 3.8e-79.
MVGHLHLQAMGDTREQSRDGLLDSPDSGLPPSPSPSPPFYALSPGTLDTRTTTEAPAAPS LFQTPPALEMRSRLLPVFFGESIEVDPEPAHEIRCNSEITYASERYFRDKIFYAPVPTVT AYSETIVAAPNCTWRSYRSQLTLEPRPRALRFGSTAIIFPKLARSSFRTTLHCSLGQPRH WYSSSLQLRRC
FAM101 |
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PFAM accession number: | PF15068 |
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Interpro abstract (IPR028215): | This protein family includes the actin regulators, Refilin A and B. Refilin (also known as Cfm or FAM101) is thought to stabilise peri-nuclear actin filament bundles, important in fibroblasts. Refilin is important as changes in localisation and shape in the nucleus plays a role in cellular and developmental processes [ (PUBMED:21709252) ]. Refilins are essential partner molecules of Filamin B involved in regulating differentiation and proliferation of chondryocytes [ (PUBMED:24436304) ]. |
GO process: | regulation of chondrocyte development (GO:0061181), actin filament bundle organization (GO:0061572) |
GO function: | filamin binding (GO:0031005) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry FAM101