The domain within your query sequence starts at position 349 and ends at position 513; the E-value for the FANCI_S2 domain shown below is 8.5e-56.



PFAM accession number:PF14676
Interpro abstract (IPR029315):

FANCI and FANCD2 form a complex central to the Fanconi anemia (FA) pathway, which is essential for the repair of DNA interstrand cross-links. FANCI has four distinct alpha solenoid (alpha-alpha superhelical) segments (S1-S4). Two mostly helical segments intervene between solenoids 1 and 2 (HD1), and between solenoids 2 and 3 (HD2) [ (PUBMED:21764741) ].

This is the solenoid 2 (S2) domain of the Fanconi anemia group I protein (FANCI).

This is a PFAM domain. For full annotation and more information, please see the PFAM entry FANCI_S2