The domain within your query sequence starts at position 349 and ends at position 513; the E-value for the FANCI_S2 domain shown below is 8.5e-56.
HVTQGLIEFGFILMDSYGPKKILDGKAVEIGTSLSKMTNQHACKLGANILLETFKIHEMI RQEILEQVLNRVVTRTSSPINHFLDLFSDIIMYAPLILQNCSKVTETFDYLTFLPLQTVQ GLLKAVQPLLKISMSMRDSLILVLRKAMFASQLDARKSAVAGFLL
FANCI_S2 |
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PFAM accession number: | PF14676 |
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Interpro abstract (IPR029315): | FANCI and FANCD2 form a complex central to the Fanconi anemia (FA) pathway, which is essential for the repair of DNA interstrand cross-links. FANCI has four distinct alpha solenoid (alpha-alpha superhelical) segments (S1-S4). Two mostly helical segments intervene between solenoids 1 and 2 (HD1), and between solenoids 2 and 3 (HD2) [ (PUBMED:21764741) ]. This is the solenoid 2 (S2) domain of the Fanconi anemia group I protein (FANCI). |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry FANCI_S2