The domain within your query sequence starts at position 37 and ends at position 184; the E-value for the GIDA domain shown below is 8.5e-56.



PFAM accession number:PF01134
Interpro abstract (IPR040131):

MnmG (also known as GidA) is a tRNA modification enzyme found in bacteria and mitochondria. MnmG forms a complex with MnmE which is involved in the formation of methyluridine derivatives at the wobble uridine base in some tRNAs [ (PUBMED:15509579) (PUBMED:11544186) (PUBMED:19767610) ].

This domain is also found in the MnmG paralogue TrmFo, a folate/FAD-dependent methyltransferase that catalyzes the methylation of the C5-uridine 54 in the T-loop of tRNAs of most Gram-positive bacteria and some Gram-negative bacteria [ (PUBMED:19416846) (PUBMED:16027442) ]. TrmFO lacks a C-terminal helical domain present in MnmG [ (PUBMED:19416846) ].

This entry represents the N-terminal domain of MnmG and related domains. This domain does not include the C-terminal region of MnmG, which contains a sterile alpha motif domain and is responsible for tRNA-protein and protein-protein interactions including association with MnmE [ (PUBMED:29870725) (PUBMED:19416846) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry GIDA