The domain within your query sequence starts at position 22 and ends at position 31; the E-value for the GnRH domain shown below is 9.2e-8.
QHWSYGLRPG
GnRH |
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PFAM accession number: | PF00446 |
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Interpro abstract (IPR002012): | The gonadotropin-releasing hormones (GnRH) (gonadoliberin) are a family of peptides that play a pivotal role in reproduction. The main function of GnRH is to act on the pituitary to stimulate the synthesis and secretion of luteinizing and follicle-stimulating hormones, but GnRH also acts on the brain, retina, sympathetic nervous system, gonads and placenta in certain species. There seems to be at least three forms of GnRH [ (PUBMED:18284378) ]. The second form is expressed in midbrain and seems to be widespread. The third form has only been found so far in fish. GnRH is a C-terminal amidated decapeptide processed from a larger precursor protein. Four of the ten residues are perfectly conserved in all species where GnRH has been sequenced. |
GO process: | multicellular organism development (GO:0007275) |
GO component: | extracellular region (GO:0005576) |
GO function: | hormone activity (GO:0005179) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry GnRH