The domain within your query sequence starts at position 404 and ends at position 499; the E-value for the Hrs_helical domain shown below is 2.2e-48.



PFAM accession number:PF12210
Interpro abstract (IPR024641):

This domain comprises the helical region of hepatocyte growth factor-regulated tyrosine kinase substrate (HRS). It is approximately 100 amino acids in length.

Hrs, together with signal transducing adaptor molecule (STAM), forms the ESCRT-0 complex, which sorts ubiquitinated cell surface receptors to lysosomes for degradation [ (PUBMED:19278655) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Hrs_helical