The domain within your query sequence starts at position 26 and ends at position 395; the E-value for the MMS22L_N domain shown below is 1.1e-199.
PPCFSCAFDNREGKFSGESYLASGALKRLILNLDPLPTNFEEDTVELFGFQWVTETALVY SCRELFHLFRQQIFNLESLVQVSCDFGKIATLHAKADSIRQQCVVFLHYIKVFIFRCLKV QEAESHSRPAHPYEALEAQLPSMLVDELRGLLLYIGHLAALPSVTVGAFVNQNQMKLFPP SWHLLHLYLDTHWLVLEILHILGEKLKQVVYGRQFIGQAGDNLTNVSLFEEHCEHLFCDL ICLSLNRFDKVMPSEALLISHCPCSCVKELWVLLIHLLDHRRKWSVADSFWNWLNKLLRT LFEKSSDQRRSSVSLTQAKDPLGFSWWISVHVASLYQIDRHGVSDKMKQMESNWSFIEEL LKRSVTVQNS
MMS22L_N |
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PFAM accession number: | PF14910 |
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Interpro abstract (IPR029425): | This entry represents the N-terminal of the MMS22L (Methyl methanesulfonate-sensitivity protein 22-like) protein. Methyl methanesulfonate-sensitivity protein 22-like (MMS22L) is a component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks [ (PUBMED:21055983) ]. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks [ (PUBMED:21055984) (PUBMED:21055985) ]. It may act by mediating the assembly of RAD51 filaments on ssDNA [ (PUBMED:21055985) ]. |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry MMS22L_N