The domain within your query sequence starts at position 108 and ends at position 162; the E-value for the Med16 domain shown below is 2.2e-12.



PFAM accession number:PF11635
Interpro abstract (IPR021665):

Mediator is a large complex of up to 33 proteins that is conserved from plants through fungi to humans - the number and representation of individual subunits varying with species [ (PUBMED:15175151) (PUBMED:15175163) ]. It is arranged into four different sections, a core, a head, a tail and a kinase-activity part, and the number of subunits within each of these is what varies with species. Overall, Mediator regulates the transcriptional activity of RNA polymerase II but it would appear that each of the four different sections has a slightly different function. Med16 is one of the subunits of the Tail portion of the Mediator complex and is required for lipopolysaccharide gene-expression [ (PUBMED:15297616) ]. Several members including the human protein, Q9Y2X0 have one or more WD40 domains on them.

GO component:mediator complex (GO:0016592)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Med16