The domain within your query sequence starts at position 64 and ends at position 226; the E-value for the Methyltransf_3 domain shown below is 1.2e-16.

HILTTLDHWSSCCEYLSHMGPVKGQILMRLVEEKAPACVLELGTYCGYSTLLIARALPPG
SRLLTVERDSRTAAVAEKVIRLAGFDEQMVELIAGSSEEVIPRLRAQHQLNRADLVLLAH
RPRYYLRDLQLLEAHALLPHGATVLADHVLFPGAPRFLQYTKS

Methyltransf_3

 Methyltransf_3
PFAM accession number:PF01596
Interpro abstract (IPR002935):

Members of this family are O-methyltransferases, including catechol O-methyltransferase [ (PUBMED:16618795) ], caffeoyl-CoA O-methyltransferase [ (PUBMED:15734921) ] and norbelladine 4'-O-methyltransferase [ (PUBMED:25061748) ]. The family includes also bacterial O-methyltransferases that may be involved in antibiotic production [ (PUBMED:8936303) (PUBMED:31147608) ].

GO function:O-methyltransferase activity (GO:0008171)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Methyltransf_3