The domain within your query sequence starts at position 1 and ends at position 238; the E-value for the Miff domain shown below is 6e-101.
MAEISRIQYEMEYTEGISQRMRVPEKLKVAPPNADLEQEFQDGVPNASVIMQVPERIVVT GNNEDISFSRPADLDLIQSTPFKPLALKTPPRVLTLSERPLDFLDLERPLPTPQSEESRA VGRLKRERSMSENAVRQNGQLVRNDSIPVLRGGSAAATSNPHHDNVRYGISNLDAAIEGA SDDMTVVDAASLRRQIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR
Miff |
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PFAM accession number: | PF05644 |
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Interpro abstract (IPR039433): | This entry represents a domain found in mitochondrial fission factor (Mff) and at the C terminus of FATE1. This domain has a predicted transmembrane segment preceded by a coiled-coil region. Despite their similarity in the C terminus, FATE1 lacks a Mff-similar N-terminal domain that is essential for interaction of Mff with the dynamin-related GTPase Drp1, which mediates mitochondrial fission. Instead, FATE1 is involved in the regulation of ER-mitochondria distance and Ca(2+) uptake by mitochondria [ (PUBMED:27402544) ]. |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry Miff