The domain within your query sequence starts at position 174 and ends at position 1145; the E-value for the Nrap domain shown below is 5e-287.

SYLLDTCMRPDINVDVAVTMPREILQDKDGLNQRYFRKRALYLAHLAYHLAQDPLFSSVR
FSYMSGCHLKPSLLLRPHGKDERLVTVRLLPCPPLDFFRPCRLLPTKNNVRSAWYRGQSC
PDYEPPTPHYNTWILQDVALETHMHLLASVLGSAQGLKDGVALLKVWLRQRELDKGLGGF
NGFIISMLVAFLVSKRKIHTTMSGYQVLRSVLQFLATTDLTINGISFSLSSDPSLPTLAE
FHQLFAVVFVDPSGRLNLCADVTASTYNQVQYEAELSMALLDSKADDGFQLLLMTPKPMI
QAFDHVVHLHPLSRLQASCHQLKLWPELQDNGGDYVSAALGPLTNILVQGLGCRLHLLAH
SRPPVPEWSINQDPPKHKDAGTLTLGFLFRPEGLTSVIDLGPEADKPEAADFRQFWGTRS
ELRRFQDGAIREAVVWEAESLFEKRLIPHQVVTHLLALHADIPDTCIQYVGGFLDALIQN
PKEISSTGEEALALAVRCYDDLSRLLWGLEGLPLTVSAVQGAHPVLRYTEVFPPAPVRPA
YSFYNRLQELASLLPRPDKPCPAYVEPMTVVCHLEGSGQWPQDAEAVQRVRAAFQLRLAE
VLTQEHRLQCCATATHTDVLKDGFVFRIRVAYQREPQILKEVRSPEGMVSLRDTPASLRL
ERDTKLLPLLTSALHGLQQQYPAYSGVARLAKRWVRAQLLGEGFTDESLDLLAASLFLHP
EPFTPPSVPQVGFLRFLYLVSTFDWKNNPLIVNLNGELTAEEQVGIRSSFLAARTQLPVM
VIITPQDRRSSVWTQDGPSAQILQQLVSLAAEALPILEKQLMDPRGPGDIRTVFRPPFDM
YDVLIHLTPRHIPRHRQAVDPPVASFCRGLLAEPGPSSLMPVLGYDPPQLYLAQLREAFE
DLALFFYDQHGGEVIGVLWKPSSFQPQPFKASSIKGRMVVSQGGELVMLPNIEAILEDFA
VLGEGLVQAVEA

Nrap

• PFAM accession number: PF03813
• Interpro abstract (IPR035082):

  Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [ (PUBMED:11895476) ]. Nrap is a large nucleolar protein (of more than 1000 amino acids). Nrap appears to be associated with ribosome biogenesis by interacting with pre-rRNA primary transcript [ (PUBMED:11895476) ].

  This domain has a nucleotidyltransferase structure.

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Nrap