The domain within your query sequence starts at position 15 and ends at position 201; the E-value for the Nucleoplasmin domain shown below is 3.7e-45.



PFAM accession number:PF03066
Interpro abstract (IPR024057):

This entry represents the core structural domain for the nucleoplasmin (Np) family of histone chaperone proteins. This core domain is formed by an 8-stranded beta barrel [ (PUBMED:15576029) ].

The three branches of the Np family, including nucleophosmin (NO38/B23), nucleoplasmin (Np), and nucleoplasmin-like proteins (NLP), bind core histones and assemble nucleosomes in vitro assays. Even though they have different histone preferences, it has been suggested that Np family members may share a general mechanism for binding histones [ (PUBMED:15576029) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Nucleoplasmin