The domain within your query sequence starts at position 302 and ends at position 320; the E-value for the OAR domain shown below is 2.3e-12.



PFAM accession number:PF03826
Interpro abstract (IPR003654):

This 14 amino acid motif has been identified within the C-terminal region of several paired-like homeodomain (HD) containing proteins [ (PUBMED:8944018) (PUBMED:9466998) ]. It was named OAR domain after the initials of otp, aristaless, and rax [ (PUBMED:9096350) ]. Although it has been proposed that this domain could be important for transactivation and be involved in protein-protein interactions or DNA binding [ (PUBMED:9096350) (PUBMED:9140395) ], its function is not yet known. Some proteins known to contain a OAR domain include human RIEG, defects in which are the cause of Rieger syndrome [ (PUBMED:8944018) ]; human OG12X and Mus musculus (Mouse) Og12x, whose function is not yet known [ (PUBMED:9466998) ]; vertebrate Rax, which plays a role in the proliferation and/or differentiation of retinal cells [ (PUBMED:9096350) ]; Drosophila DRX, which appears to be important in brain development [ (PUBMED:9482887) ]; and human SHOX, encoded by the short stature homeobox-containing gene.

This is a PFAM domain. For full annotation and more information, please see the PFAM entry OAR