The domain within your query sequence starts at position 101 and ends at position 245; the E-value for the PI31_Prot_N domain shown below is 9.6e-31.



PFAM accession number:PF11566
Interpro abstract (IPR021625):

PI31 is a regulatory subunit of the immuno-proteasome which is an inhibitor of the 20S proteasome in vitro. PI31 is also an Fbxo7. Skp1 binding partner. Fbxo7 is an F-box protein, which are the substrate-recognition components of the Skp1-Cul1-F box protein (SCF) E3 ubiquitin ligases. The interaction between PI31 and Fbxo7.Skp1 occurs via the beta sheets of a N-terminal domain present in both proteins and known as FP(Fbxo7/PI31) domain. The structure of PI31 FP domain contains a novel alpha/beta-fold and two intermolecular contact surfaces. This entry represents the N-terminal domain of the PI31 proteasome regulator [ (PUBMED:18495667) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry PI31_Prot_N