The domain within your query sequence starts at position 197 and ends at position 227; the E-value for the PPR domain shown below is 2.3e-4.



PFAM accession number:PF01535
Interpro abstract (IPR002885):

This entry represents the PPR repeat.

Pentatricopeptide repeat (PPR) proteins are characterised by tandem repeats of a degenerate 35 amino acid motif [ (PUBMED:10664580) ]. PPR proteins are sequence-specific RNA-binding proteins that are involved in multiple aspects of RNA metabolism [ (PUBMED:18031283) (PUBMED:22576772) ]. They can bind a diversity of sequences that confers the variability in its functions [ (PUBMED:30125002) ]. Most have roles in mitochondria or plastids [ (PUBMED:15270678) ]. PPR repeats were discovered while screening Arabidopsis proteins for those predicted to be targeted to mitochondria or chloroplast [ (PUBMED:10664580) (PUBMED:15269332) ]. Some of these proteins have been shown to play a role in post-transcriptional processes within organelles [ (PUBMED:12782738) (PUBMED:12832482) ]. Plant genomes have between one hundred to five hundred PPR genes per genome whereas non-plant genomes encode two to six PPR proteins.

The plant PPR protein family has been divided in two subfamilies on the basis of their motif content and organisation [ (PUBMED:15269332) (PUBMED:17560114) ].

The crystal structure of maize chloroplast PPR10 has been reported. The nineteen repeats of PPR10 are assembled into a right-handed superhelical spiral. PPR10 forms a homodimer and exhibits considerable conformational changes upon binding to its ssRNA target, with six nucleotides being specifically recognized by six corresponding PPR10 repeats [ (PUBMED:24162847) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry PPR