The domain within your query sequence starts at position 536 and ends at position 773; the E-value for the RINT1_TIP1 domain shown below is 3.1e-11.



PFAM accession number:PF04437
Interpro abstract (IPR007528):

This entry includes PINT-1 from animals, Tip20 from yeasts and MAIGO2 (Mag2) from plants. They play a role in anterograde transport from the endoplasmic reticulum (ER) to the Golgi and/or retrograde transport from the Golgi to the ER share sequence similarity. They share a similar domain organisation with an N-terminal leucine heptad repeat rich coiled coil and an ~500-residue C-terminal RINT1/TIP20 domain, which might be a protein-protein interaction module necessary for the formation of functional complexes.

RINT-1 interacts with Rad50 only during late S and G2/M phases and participates in radiation induced checkpoint control [ (PUBMED:11096100) ]. RINT-1 also functions in membrane trafficking from the endoplasmic reticulum(ER) to the Golgi complex in interphase cells [ (PUBMED:11096100) (PUBMED:16600870) (PUBMED:16571679) ].

Tip20 is involved in the retrograde transport from the Golgi to the ER [ (PUBMED:19151722) (PUBMED:8334998) ].

Arabidopsis Mag2 functions in the transport of storage protein precursors between the ER and Golgi complex in plants [ (PUBMED:17194767) ].

GO process:Golgi vesicle transport (GO:0048193)
GO component:endoplasmic reticulum (GO:0005783)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry RINT1_TIP1