The domain within your query sequence starts at position 285 and ends at position 433; the E-value for the Radial_spoke domain shown below is 4.6e-53.



PFAM accession number:PF04712
Interpro abstract (IPR006802):

This family includes the radial spoke head proteins RSP4 and RSP6 from Chlamydomonas reinhardtii, and several eukaryotic homologues, including mammalian RSHL1, the protein product of a familial ciliary dyskinesia candidate gene [ (PUBMED:11237735) ]. The radial spoke head proteins are important in maintaining normal movement in motile, "9+2"-structure cilia and flagella. Mutations of the human RSPH9 and RSPH4A genes have been linked to primary ciliary dyskinesia, a genetically heterogeneous inherited disorder arising from dysmotility of motile cilia and sperm [ (PUBMED:19200523) ]. RSPH6A has also been shown to be required for sperm flagellum formation and male fertility in mice [ (PUBMED:30185526) ].

GO process:cilium assembly (GO:0060271), cilium movement involved in cell motility (GO:0060294)
GO component:radial spoke (GO:0001534)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Radial_spoke