The domain within your query sequence starts at position 153 and ends at position 210; the E-value for the Synaptobrevin domain shown below is 2.1e-9.
SILHSAADSVTSAVQKASQALNERGERLGRAEEKTEDMKNSAQQFAETAHKLAMKHKC
Synaptobrevin |
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PFAM accession number: | PF00957 |
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Interpro abstract (IPR001388): | Synaptobrevin is an intrinsic membrane protein of small synaptic vesicles [ (PUBMED:2560644) ], specialised secretory organelles of neurons that actively accumulate neurotransmitters and participate in their calcium-dependent release by exocytosis. Vesicle function is mediated by proteins in their membranes, although the precise nature of the protein-protein interactions underlying this are still uncertain [ (PUBMED:1976629) ]. Synaptobrevin may play a role in the molecular events underlying neurotransmitter release and vesicle recycling and may be involved in the regulation of membrane flow in the nerve terminal, a process mediated by interaction with low molecular weight GTP-binding proteins [ (PUBMED:8406010) ]. Synaptic vesicle-associated membrane proteins (VAMPs) from Torpedo californica (Pacific electric ray) and SNC1 from yeast are related to synaptobrevin. |
GO process: | vesicle-mediated transport (GO:0016192) |
GO component: | integral component of membrane (GO:0016021) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry Synaptobrevin