The domain within your query sequence starts at position 425 and ends at position 452; the E-value for the Tcell_CD4_C domain shown below is 2.2e-18.



PFAM accession number:PF12104
Interpro abstract (IPR021963):

This domain is the C-terminal domain of the CD4 T cell receptor. The C-terminal domain is the cytoplasmic domain which relays the signal for T cell activation. This process involves co-receptor internalisation. This domain is involved in binding to the N-terminal of Lck co-receptor in a Zn2+ clasp structure.

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Tcell_CD4_C