The domain within your query sequence starts at position 782 and ends at position 954; the E-value for the Uso1_p115_C domain shown below is 1.6e-12.



PFAM accession number:PF04871
Interpro abstract (IPR006955):

This domain identifies a group of proteins, which are described as: General vesicular transport factor, Transcytosis associate protein (TAP) and Vesicle docking protein. This myosin-shaped molecule consists of an N-terminal globular head region, a coiled-coil tail which mediates dimerisation, and a short C-terminal acidic region [ (PUBMED:11927603) ]. p115 tethers COP1 vesicles to the Golgi by binding the coiled coil proteins giantin (on the vesicles) and GM130 (on the Golgi), via its C-terminal acidic region. It is required for intercisternal transport in the Golgi stack. This domain is found in the acidic C-terminal region, which binds to the golgins giantin and GM130. p115 is thought to juxtapose two membranes by binding giantin with one acidic region, and GM130 with another [ (PUBMED:12077354) ].

GO process:vesicle-mediated transport (GO:0016192), intracellular protein transport (GO:0006886)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Uso1_p115_C