The domain within your query sequence starts at position 50 and ends at position 122; the E-value for the Xan_ur_permease domain shown below is 4.6e-12.



PFAM accession number:PF00860
Interpro abstract (IPR006043):

This entry represents a susbset of the wider APC (Amino acid-Polyamine-organoCation) superfamily of transporters [ (PUBMED:10931886) ]. Characterised proteins in this entry include:

  • Xanthine permease PbuX, involved in cellualar xanthine transport [ (PUBMED:9098051) ]
  • Uric acid permeases which promotes uptake of uric acid into the cell in limiting-nitrogen conditions [ (PUBMED:11344136) ]
  • Uracil permease [ (PUBMED:8206848) ]
  • Sodium-dependent vitamin C transporter, a sodium/ascorbate cotransporter mediating electrogenic uptake of Vitamin C [ (PUBMED:11396616) ]

These proteins generally contain 12 transmembrane regions. Many members of this family are uncharacterised and may transport other substrates eg. RutG is likely to transport pyrimidines into the cell [ (PUBMED:16540542) ].

GO process:transmembrane transport (GO:0055085)
GO component:membrane (GO:0016020)
GO function:transmembrane transporter activity (GO:0022857)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Xan_ur_permease