The domain within your query sequence starts at position 20 and ends at position 114; the E-value for the Yippee-Mis18 domain shown below is 6.8e-20.



PFAM accession number:PF03226
Interpro abstract (IPR004910):

This domain is found in both Yippee-type proteins and Mis18 kinetochore proteins. Yippee are putative zinc-binding/DNA-binding proteins [ (PUBMED:11240639) ]. Mis18 are proteins involved in the priming of centromeres for recruiting CENP-A [ (PUBMED:17199038) (PUBMED:22264723) ]. Mis18-alpha and beta form part of a small complex with Mis18-binding protein. Mis18-alpha is found to interact with DNA de-methylases through a Leu-rich region located at its carboxyl terminus [ (PUBMED:22552327) ]. This domain includes the CULT domain from proteins such as Cereblon [ (PUBMED:25569776) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Yippee-Mis18