The domain within your query sequence starts at position 24 and ends at position 49; the E-value for the RPEL domain shown below is 1.36e-8.
DYLKRKIRSRPERAELVRMHILEETS
RPELRepeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2 |
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SMART accession number: | SM00707 |
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Description: | - |
Interpro abstract (IPR004018): | RPEL repeat (RPxxxEL) containing proteins are found in a wide range of metazoan organisms. RPEL repeats have been shown to be required for unpolymerised actin binding and proteins containing RPEL repeats are able to modify cell shape and/or are important in the regulation of gene expression by the actin cytoskeleton. RPEL repeats can be found in association with the SAP motif, which could be involved in DNA binding [ (PUBMED:12732141) (PUBMED:15620697) ]. Some proteins known to contain RPEL repeats are listed below:
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Family alignment: |
There are 16001 RPEL domains in 4997 proteins in SMART's nrdb database.
Click on the following links for more information.
- Evolution (species in which this domain is found)
- Structure (3D structures containing this domain)
- Links (links to other resources describing this domain)