The domain within your query sequence starts at position 1204 and ends at position 1376; the E-value for the RPT_1 domain shown below is 4.27e-16.

DPEQIRMSGMGPCPQRSPKEHSLSFRYKEFEEKVPSCVNTQGTHDEHPNSVKRRGFDHVP
TATGNNHSHNYKVIRGKQQSGRADLRACDPGRIKKKSGMAGCTHTCPDGYNFLFRYRIIG
NNEQPGIVLRACDPHQNTEERMCHGQPVSPNVNHLVKHRKNGGQHQSGVTAQG

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.