The domain within your query sequence starts at position 1378 and ends at position 1488; the E-value for the RPT_1 domain shown below is 5.43e-6.

ALDEENKPGGQQDKTSEQKGRDLDKKDTAVELGKGPEPKGKDLYLEDQGLAEKDKALEQR
GAALQQTQAPEPRARAQEHRDLEQKDEHLELRDKTPEEKDKVLVLEDRAPE

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.