The domain within your query sequence starts at position 148 and ends at position 213; the E-value for the RPT_1 domain shown below is 2.48e-5.

SGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYH
LTHTER

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.