The domain within your query sequence starts at position 160 and ends at position 277; the E-value for the RPT_1 domain shown below is 4.9e-5.

GGQGRPRLPGALPPSEAGLPAPSTRPPLLSSEVPQVPPLEGLPLSQSALSIAKEKNISLQ
TAIAIEALTQLSSALPQPSHSTSQASCPLPEALSPSAPFRSPQSYLRAPSWPVVPPEE

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.