The domain within your query sequence starts at position 1755 and ends at position 1804; the E-value for the RPT_1 domain shown below is 3.99e-5.

PQPKSLGSGQCVPEPSPSGQRPYPEVFYGSPGPPNSQVSGGAPIDSQLHP

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.