The domain within your query sequence starts at position 1882 and ends at position 2038; the E-value for the RPT_1 domain shown below is 6.61e-9.

DGKLSFWGEHTGQLYSKFLLKAEPLALIVSHDYKGSTSHSLPYESSISTALEHTVSALLT
PAEQTSTWKFKTKLNDKVYSQDFEAYNTKDKIGVELSGRADLSGLYSPIKLPFFYSEPVN
VLNGLEVNDAVDKPQEFTIIAVVKYDKNQDVHTINLP

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.