The domain within your query sequence starts at position 209 and ends at position 375; the E-value for the RPT_1 domain shown below is 2.52e-18.

QPFEYNETGQGFCEEVALCTSQNSQLGETLYKHTECGRTFVDSLKLSVSQKTRLHTELHE
CSICRKSFYVDLQFGHHTALSGSSPYERNEYEKLFCDGTAFIVHQEAYTRKIAQEYKVSN
RTWGKPALFKHQIIQMGGKPYEYYENRKNFSKKSHPTQPRRPHVGEK

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.