The domain within your query sequence starts at position 213 and ends at position 280; the E-value for the RPT_1 domain shown below is 8.77e-8.

KVVKTGPSGHNIRSCPNLRGIPIGMLVLGNKVKAVGEVTNSEGAWVQLDKNSMVEFCESD
EGEAWSLA

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.