The domain within your query sequence starts at position 233 and ends at position 315; the E-value for the RPT_1 domain shown below is 2.35e-20.

GSVLTMGSVLTTGSVLTIGSVLTTGSVLTMGSVLTTGSVLTAGSVLTMGSVLTAGSVLTM
GSVLTAGAVLPAGSVLTMGSVLT

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.